Amy Schumer Says Botched Colonoscopy Left Her Not Feeling Sexual
amy schumer said a botched colonoscopy left her “not feeling very sexual,” a blunt new line from a performer who has spent the past year talking openly about health. She made the comment during a Not Skinny But Not Fat podcast event with Dear Media.
Schumer at 44
“I actually had, kind of, a botched colonoscopy, so I’m not feeling very sexual,” Schumer said at the event. She is 44 years old, and the remark landed as another update in a run of health disclosures that have already included exogenous Cushing syndrome, steroid injections and perimenopause treatment.
“I feel happier than I’ve ever been before,” she also said during the same event, setting up a sharper contrast between how she described her mood and how she described the procedure’s aftermath. For a public figure who has tied her recent body and hormone changes to medical treatment, the line gives a concrete snapshot of where she says she is now.
2025 Health Timeline
In 2025, Schumer said on the Call Her Daddy podcast that she had been getting steroid injections and that they gave her Cushing syndrome. She also said in a March 2025 social media video that she tried Wegovy three years earlier and could not handle it because she was puking.
In that same March 2025 video, she said Midi Health put her on estrogen and progesterone because she realized she was in perimenopause, then added that her hair was fuller, her skin was better, she had more energy and she wanted to get down more. She closed that update by saying, “My hair is fuller, my skin is better, I have more energy, I want to get down more, if you know what I mean. I’m talking about sex. So that’s been great and Mounjaro’s been great.”
Chris Fischer and Gene
Schumer is currently separated from her estranged husband, Chris Fischer, and they share a son named Gene. That personal context sits behind the latest comment without changing the practical takeaway: she is still using her public appearances to describe medical treatment, side effects and how they are affecting her day to day.
For readers tracking Schumer’s health narrative, the useful detail is not the label on the procedure but the effect she attached to it. The comedian framed it as one more body issue in a longer chain of hormone and medication updates, and she did so in her own words, without softening the result.
