Colorado vs Oklahoma State is set for Saturday, October 24, 2026, with the Big 12 matchup scheduled for 7:00 PM EDT at Boone Pickens Stadium in Stillwater, Oklahoma. The game brings together a 4-2 Oklahoma State team that has been strong at home and a Colorado squad trying to stop a four-game losing streak.
Oklahoma State has leaned on the passing game
The Cowboys enter at 4-2 overall and 3-0 at home, and their offense has been one of the more productive attacks in the conference. Through six games, Oklahoma State is averaging 37.1 points per game, 517.6 yards per game and 329.5 passing yards per game. That output has helped the Cowboys establish a clear home-field advantage heading into this one.
Drew Mestemaker has been the driver of that success. The Oklahoma State quarterback leads the team with 1,940 passing yards and 16 touchdown passes through six games, giving the Cowboys the kind of high-volume passing production that can pressure an opponent early and often. With Mestemaker setting the pace, Oklahoma State has also produced 17 passing touchdowns as a team.
Colorado is looking to steady its season
Colorado comes in at 2-4 overall and has struggled to find consistency. The Buffaloes have allowed the season to drift because of scoring problems and turnover issues, and they enter Stillwater with a minus-5 turnover margin. They have also committed 55 penalties, a number that has added to the difficulty of building momentum.
Even so, Colorado still has a passing game that can generate yards. The Buffaloes are averaging 253.8 passing yards per game, and their quarterback, Lewis, has thrown for 733 yards with 6 touchdown passes. The issue has been translating that production into enough points, as Colorado is scoring 19.5 points per game and sitting on a four-game losing streak.
What to watch in Stillwater
This matchup gives Oklahoma State a chance to keep rolling at home against a Colorado team that has had trouble finishing drives and protecting the football. The Cowboys’ offense has been efficient, explosive and productive through the air, while Colorado will need a cleaner performance to stay competitive.
The key question is whether Colorado can slow Oklahoma State enough to make this a game into the second half. If it cannot, Mestemaker and the Cowboys have the kind of passing profile that can quickly turn a Saturday night home game into a one-sided result.
