College Football Week 7: Northwestern vs. Penn State Predictions and Top Bets
In an upcoming College Football Week 7 matchup, the Penn State Nittany Lions host the Northwestern Wildcats. After a surprising loss to UCLA, Penn State seeks to regain momentum at home. Currently, the Nittany Lions are favored by 21.5 points, with the total points set between 47.5 and 48.5, depending on the sportsbook used.
Northwestern vs. Penn State Predictions and Best Bets
- Northwestern +22.5: -115 at FanDuel
- Over 47.5 points: -115 at BetMGM
Oddsmakers believe that Penn State will dominate this game. However, their recent form raises questions. The Nittany Lions have struggled defensively, allowing 199 rushing yards per game in their last three contests. This trend could pose challenges against Northwestern’s strong ground game.
Northwestern’s Strengths
The Wildcats possess the 19th-highest run grade and 11th-highest run block grade in the nation. This capability may exploit Penn State’s defensive weaknesses. In their last outing, UCLA—ranked 93rd in rushing yards per game—managed to score 42 points against the Nittany Lions.
Penn State’s Defensive Challenges
Historically, Penn State’s defense has been formidable. However, their recent performances suggest a decline. The Nittany Lions have participated in more high-scoring games lately, achieving a 4-1 over record in 2025. The Wildcats aim to continue this trend, particularly with quarterback Preston Stone’s improved form since his rocky start against Tulane in Week 1.
Moneyline Odds Analysis
Why Penn State Could Win
- Best odds: -1600 at DraftKings
- Home advantage with 16 wins in the last 19 games
- Elite secondary to counter Northwestern’s ground game
Penn State’s roster boasts superior talent over Northwestern’s lineup. Despite recent setbacks, they are positioned to exploit the Wildcats’ vulnerabilities. If they can effectively manage their defensive strategies, a victory seems likely.
Why Northwestern Could Win
- Best odds: +1050 at Caesars
- Possesses a talented and physical ground game
- Penn State struggling against the run
Although Penn State has faltered recently, Northwestern could capitalize on these challenges. Their run-heavy approach may allow them to keep the game competitive if they manage to utilize their physicality effectively.
The fans can expect an engaging matchup this Saturday as both teams showcase their strengths and seek a much-needed victory in this pivotal college football week.
