NFL Week 16: 2025 Picks and Score Predictions for Every Game
The NFL’s Week 16 promises critical matchups as teams strive for playoff positions. The regular season is nearing its end, and the stakes are high. Few expected the playoffs to occur without major stars like Lamar Jackson, Joe Burrow, and Patrick Mahomes. Meanwhile, the playoffs in both conferences remain fiercely competitive.
NFL Week 16: Key Matchups and Predictions
As all 32 teams return from bye weeks, this week features enticing games. Here are the highlights for Week 16, including predictions for each matchup.
Los Angeles Rams at Seattle Seahawks
Date: Thursday, December 18th, 8:15 PM ET
This matchup showcases two 11-3 teams from the NFC West, vying for the division title. The Rams previously defeated the Seahawks, but Sam Darnold’s four interceptions in that game raised concerns about Seattle’s offensive performance.
- Current Standings: Rams hold the top seed, while Seahawks occupy the fifth seed.
- Playoff Implications: A win secures home-field advantage for the Rams.
With the game taking place in Seattle, home-field advantage plays a significant role. However, the Rams face a potential absence of key player Davante Adams. This could impact their overall performance.
Darnold’s inconsistency in high-pressure situations is another factor to consider. Overall, while this game feels like a toss-up, I predict the Rams will edge out the Seahawks.
Prediction: Rams win 23-21
For NFL Week 16, teams are eager to clinch playoff spots. The competition is fierce, with every game holding crucial importance for postseason aspirations.
