December 2025: Investigation Continues in Salmonella Outbreak

As the investigation into the Salmonella outbreak continues, health officials are focusing on the food source of the infections. On December 23, 2025, the Centers for Disease Control and Prevention (CDC) reported that 64 individuals from 22 states tested positive for the outbreak strain of Salmonella Telelkebir. The investigation points to raw oysters as a potential source of contamination.

Key Facts about the Outbreak

The timeline of illnesses linked to the outbreak spans from June 21 to November 28, 2025. The data collected so far indicates that:

• 64 confirmed cases of Salmonella have been recorded.
• 22 states are involved in this outbreak.
• Of the 44 individuals for whom information is available, 20 were hospitalized.
• No fatalities have been reported.

It’s important to note that the actual number of cases is likely higher. Many people recover without medical attention and don’t get tested for Salmonella. Furthermore, recent cases may still be underreported, as it typically takes three to four weeks to confirm if someone is part of the outbreak.

Demographic Insights

Public health officials are conducting interviews to gather additional data from those infected. Key demographic information includes:

• Median age: 52 years
• Age range: 10 to 76 years
• Racial breakdown: 85% White, 12% African American/Black, 2% Native Hawaiian or other Pacific Islander
• 95% non-Hispanic and 5% Hispanic

Out of 27 individuals who were interviewed, a significant 74% reported consuming raw oysters before falling ill. This figure starkly contrasts with just 1.6% from the FoodNet Population Survey, suggesting a strong link between raw oysters and the outbreak.

Laboratory Investigations

Using the PulseNet system, health investigators are identifying potential cases related to the outbreak. PulseNet maintains a national database of DNA fingerprints of foodborne illness-causing bacteria. Whole genome sequencing (WGS) revealed that the bacteria from patient samples are genetically similar, indicating that they likely originated from the same source.

Analysis of samples from 59 infected individuals showed no antibiotic resistance in the bacteria. For more detailed information, the National Antimicrobial Resistance Monitoring System (NARMS) provides additional insights.

Public Health Recommendations

Health officials advise that raw oysters can potentially harbor harmful bacteria year-round. To mitigate the risk of foodborne illness, it is crucial to cook oysters thoroughly before consumption.

The investigation remains ongoing, and public health authorities will continue to monitor and collect data on this salmonella outbreak.