Greg Peterson’s Top MLB Picks for Friday, April 3

Bassyonni

Published: April 3, 2026 11:26 AM ET

On Friday, April 3, MLB expert Greg Peterson has released his top picks for the day’s games, providing insights into important matchups across the league. These selections consider the strengths and weaknesses of starting pitchers, bullpens, and offensive capabilities.

Top MLB Picks for Friday, April 3

Miami Marlins vs. New York Yankees

The Yankees will face the Marlins at 1:35 PM Eastern. Yankees pitcher Will Warren has struggled, holding a 4.44 ERA. He allows an average of 1.2 home runs and issues 3.6 walks per nine innings. The Yankees’ lineup, however, was potent last season, averaging 5.2 runs per game.

Marlins pitcher Eury Perez has demonstrated strong home performance, with a 2.93 ERA at home but a notable drop to a 5.33 ERA on the road.

Pick: Yankees vs. Marlins Over 8 Runs (Greg’s Handicapped Total: 8.7)

Toronto Blue Jays vs. Chicago White Sox

Starting at 2:10 PM Eastern, the Blue Jays will take on the White Sox. Blue Jays pitcher Dylan Cease had an impressive debut with 12 strikeouts in 5 1/3 innings. However, he often struggles with pitch count management, evidenced by a 4.55 ERA last season.

The White Sox will begin with an opener followed by Sean Burke, who had a 4.22 ERA and walked 4.2 batters per nine innings last year.

Pick: Blue Jays vs. White Sox Over 7.5 Runs (Greg’s Handicapped Total: 8.4)

Tampa Bay Rays vs. Minnesota Twins

The Rays meet the Twins at 4:10 PM Eastern. Twins pitcher Bailey Ober posted a 5.10 ERA last season, allowing 1.8 home runs per nine innings. Rays pitcher Joe Boyle showed promise with 10 strikeouts per nine innings but struggled with command, resulting in a 4.67 ERA.

Pick: Rays vs. Twins Over 7.5 Runs (Greg’s Handicapped Total: 8.2)

Philadelphia Phillies vs. Colorado Rockies

This matchup at Coors Field is set for 4:10 PM Eastern, known for its offensive elevation. Last season, the Rockies averaged 4.6 runs at home compared to only 2.8 runs away. Aaron Nola, of the Phillies, comes off a tough 2025 season with a 6.01 ERA. Rockies starter Michael Lorenzen had a 4.64 ERA last season.

Pick: Phillies vs. Rockies Over 10 Runs (Greg’s Handicapped Total: 11.1)

Seattle Mariners vs. Los Angeles Angels

At 9:38 PM Eastern, the Mariners will face the Angels. Mariners pitcher Bryan Woo hit a 2.93 ERA last season and had 9.5 strikeouts per nine innings. The Angels, led by Reid Detmers, have a strong offense ranked fourth in home runs per at-bat last year.

Pick: Mariners vs. Angels Over 8 Runs (Greg’s Handicapped Total: 8.7)

Houston Astros vs. Oakland Athletics

The final game of the day features the Astros against the Athletics at 9:40 PM Eastern. Cristian Javier of the Astros holds a 4.62 ERA from last season. The Athletics’ Jeffrey Springs recorded a 4.11 ERA and will benefit from playing at home for the second consecutive year.

Pick: Athletics Moneyline +100 and Under 10.5 Runs (Greg’s Handicap: Athletics -122 and Total 9.7)

Fans and bettors alike can follow these matchups and utilize Peterson’s analysis for informed decisions throughout the day. The importance of understanding pitcher statistics and team performance cannot be overstated when making predictions in Major League Baseball.